Fragile X Syndrome

  • Fragile X syndrome is a genetic condition caused by an altered gene on the X chromosome
  • It is the most common inherited cause of intellectual disabilities

"Fragile X Explained" - video (Yahoo News with Katie Couric)

Signs & Symptoms:

  • Physical features:
    • Elongated face
    • Prominent ears
    • Flat feet
    • Poor muscle tone
    • High arched palate
    • Frequent ear infections
    • Loose joints
  • Behavioral features:
    • Attention deficit/impulsivity/hyperactivity
    • Learning disabilities
    • Poor eye contact
    • Autistic-like behavior
    • Social anxiety
    • Sensory integration problems, such as hypersensitivity to loud noises or bright lights
    • Speech delay, with expressive language more severely affected than receptive language
  • Seizures (epilepsy) affect about 25% of people with Fragile X

Sources: NYS Office for People with Developmental Disabilities; FRAXA Research Foundation (2011)